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Mononucleosis Plan


Monospot test

EBV antibody consider if high suspicion, negative monospot test

Serology for CMV, toxoplasmosis, VIH, hepatitis A-B-C, syphilis

Throat culture

Leave of absence

Adequate hydratation

Acetaminophen, NSAIDs

Prednisone 30-50 mg orally daily tapered over 10-14 days or Dexamethasone 0.3 mg/kg (up to 10 mg) oral for severe odynophagia or airway compromise

Avoid strenuous exercise and contact sports x 3-4 weeks

Follow up in 2 weeks, or before if worsen, airway obstruction, LUQ pain

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